English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Plus monthly

Global: Zendy Tools annual

Global: Zendy Tools monthly

Global: Zendy Free Plan

Spin-echo functional MRI (SE-fMRI) has the potential to improve spatialspecificity when compared to gradient-echo fMRI. However, high spatiotemporalresolution SE-fMRI with large slice-coverage is challenging as SE-fMRI requiresa long echo time (TE) to generate blood oxygenation level-dependent (BOLD)contrast, leading to long repetition times (TR). The aim of this work is todevelop an acquisition method that enhances the slice-coverage of SE-fMRI athigh spatiotemporal resolution. An acquisition scheme was developed entitledMultisection Excitation by Simultaneous Spin-echo Interleaving (MESSI) withcomplex-encoded generalized SLIce Dithered Enhanced Resolution (cgSlider).MESSI utilizes the dead-time during the long TE by interleaving the excitationand readout of two slices to enable 2x slice-acceleration, while cgSliderutilizes the stable temporal background phase in SE-fMRI to encode and decodetwo adjacent slices simultaneously with a phase-constrained reconstructionmethod. The proposed cgSlider-MESSI was also combined with SimultaneousMulti-Slice (SMS) to achieve further slice-acceleration. This combined approachwas used to achieve 1.5mm isotropic whole-brain SE-fMRI with a temporalresolution of 1.5s and was evaluated using sensory stimulation and breath-holdtasks at 3T. Compared to conventional SE-SMS, cgSlider-MESSI-SMS providesfour-fold increase in slice-coverage for the same TR, with comparable temporalsignal-to-noise ratio. Corresponding fMRI activation from cgSlider-MESSI-SMSfor both fMRI tasks were consistent with those from conventional SE-SMS.Overall, cgSlider-MESSI-SMS achieved a 32x encoding-acceleration by combiningRinplanexMBxcgSliderxMESSI=4x2x2x2. High-quality, high-resolution whole-brainSE-fMRI was acquired at a short TR using cgSlider-MESSI-SMS.

Accelerated spin-echo fMRI using Multisection Excitation by Simultaneous  Spin-echo Interleaving (MESSI) with complex-encoded generalized SLIce  Dithered Enhanced Resolution (cgSlider) Simultaneous Multi-Slice Echo-Planar  Imaging