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In this paper, we obtain exact solutions of the following rational differenceequation  $ x_{n+1}=\frac{x_{n}x_{n-2}x_{n-4}}{x_{n-1}x_{n-3}(a_{n}+b_{n}x_{n}x_{n-2}x_{n-4})}, $ where $a_{n}$ and $b_{n}$are random real sequences, by using the technique of Lie symmetry analysis.Moreover, we discuss the periodic nature and behavior of solutions for somespecial cases. This work is a generalization of some works by Elsayed andIbrahim in [E.M.Elsayed, T. F. Ibrahim, { Solutions and periodicity of arational recursive sequences of order five}, Bulletin of the MalaysianMathematical Sciences Society 38:1 (2015), 95-112].

General form of the solutions of some difference equations via Lie symmetry analysis