English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Plus monthly

Global: Zendy Tools annual

Global: Zendy Tools monthly

Global: Zendy Free Plan

Over the last decade one of the most significant technological advances madein the field of radiation detectors for nuclear medicine was the development ofSilicon Photomultipler (SiPM) sensors. At present a only small number of SiPMbased radiation detectors for Single Photon Emission Computed Tomography(SPECT) applications have been explored, and even fewer experimental prototypesdeveloped. An in-silico investigation into the optimal design of a PhilipsDPC3200 SiPM photosensor-based thin monolithic scintillator detector for SPECTapplications was undertaken using the Monte Carlo radiation transport modellingtoolkit Geant4 version 10.5. The performance of the 20 different SPECTradiation detector configurations, 4 scintillator materials (NaI(Tl), GAGG(Ce),CsI(Tl) and LaBr$_{3}$(Ce)) and 5 thicknesses (1 to 5 mm), were determinedthrough the use of seven figures of merit. It was found that a crystalthickness range of 4 to 5 mm was required for all four materials to ensureacceptable energy resolution, sensitivity and spatial resolution performancewith the Philips DPC3200 SiPM. Any thinner than this and the performance of allfour materials was found to degrade rapidly due to a high probability ofmaterial specific fluorescence x-ray escape after incident gamma/x-rayphotoelectric absorption. When factoring in each material's magnetic resonanceimaging compatibility, hygroscopy, and cost, it was found that CsI(Tl)represents the most promising material to construct tileable Philips digitalSiPM based thin monolithic scintillator detectors for SPECT applications.

In-Silico Optimisation of Tileable Philips Digital SiPM Based Thin Monolithic Scintillator Detectors for SPECT Applications