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We consider the minimum extension of the SM denominated 2HDM-III, in which,itnew coupling constants to the new Higgs field in the Lagrangian of Yukawa areadded furtheremore a Majorana mass in generated via See-Saw mechanism SSM-Ithus, the effective masses of the Dirac and Majorana neutrinos will besensitive to te VEV of Higgs doublets and to the structure of the Yukawaconstants. Then we consider the MSS-III,in which a $Z_{2}$ symmetry is imposedto Lagrangian 2HDM-III to attach a doublet to the particles of the SM, and theother doublet to the triplet of fermions included in this mechanism. Finally,the MSS-I+III is simultaneously implemented in the M2DH-III. This is importantbecause the additional heavy fermions in the adjoint representation of the weakisoespin group $SU(2)$ allows them to interact with the gauge bosons,facilitating their production in the colliding experiments.

See-Saw Mechanism in the 2HDM through the simultaneous introduction of a singlet and triplet of Majorana