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The main purpose of this study is to show that a highly accelerated CartesianMRF scheme using a multi-shot EPI readout (i.e. multi-shot EPI-MRF) can producegood quality multi-parametric maps such as T1, T2 and proton density (PD) in asufficiently short scan duration that is similar to conventional MRF. Thismulti-shot approach allows considerable subsampling while traversing the entirek-space trajectory, can yield better SNR, reduced blurring, less distortion andcan also be used to collect higher resolution data compared to existingsingle-shot EPI-MRF implementations. The generated parametric maps are comparedto an accelerated spiral MRF implementation with the same acquisitionparameters to evaluate the performance of this method. Additionally, aniterative reconstruction algorithm is applied to improve the accuracy ofparametric map estimations and the fast convergence of EPI-MRF is alsodemonstrated.

Balanced multi-shot EPI for accelerated Cartesian MRF: An alternative to spiral MRF