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The objective of this study was to investigate the relationship betweenerectile pressure (EP) and shear wave speed of the corpus cavernosa obtainedvia a specific ultrasound vibro-elastography (UVE) technique. This study buildsupon our prior investigation, in which UVE was used to evaluate theviscoelastic properties of the corpus cavernosa in the flaccid and erectstates. A two-dimensional poroviscoelastic finite element model (FEM) wasdeveloped to simulate wave propagation in the penile tissue according to ourexperimental setup. Various levels of EP were applied to the corpus cavernosa,and the relationship between shear wave speed in the corpus cavernosa and EPwas investigated. Results demonstrated non-linear, positive correlationsbetween shear wave speeds in the corpus cavernosa and increasing EP atdifferent vibration frequencies (100-200 Hz). These findings represent thefirst report of the impact of EP on shear wave speed and validates the use ofUVE in the evaluation of men with erectile dysfunction. Further evaluations arewarranted to determine the clinical utility of this instrument in the diagnosisand treatment of men with erectile dysfunction.

A Numerical Study of the Relationship Between Erectile Pressure and Shear Wave Speed of Corpus Cavernosa in Ultrasound Vibro-elastography