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We discuss the role of water bridging the DNA-enzyme interaction by resortingto recent results showing that London dispersion forces between delocalizedelectrons of base pairs of DNA are responsible for the formation of dipolemodes that can be recognized by \textit{Taq} polymerase. We describe thedynamic origin of the high efficiency and precise targeting of \textit{Taq}activity in PCR. The spatiotemporal distribution of interaction couplings,frequencies, amplitudes, and phase modulations comprise a pattern of fieldswhich constitutes the electromagnetic image of DNA in the surrounding water,which is what the polymerase enzyme actually recognizes in the DNA waterenvironment. The experimental realization of PCR amplification, achievedthrough replacement of the DNA template by the treatment of pure water withelectromagnetic signals recorded from viral and bacterial DNA solutions, isfound consistent with the gauge theory paradigm of quantum fields.

Water Bridging Dynamics of Polymerase Chain Reaction in the Gauge Theory Paradigm of Quantum Fields