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The need for affordable and appropriate medical technologies for developingcountries continue to rise as challenges such as inadequate energy supply,limited technical expertise and poor infrastructure persists. Low-field MRI isa technology that can be tailored to meet specific imaging needs within suchcountries. Its low power requirements and the possibility of operating inminimally shielded or unshielded environments make it especially attractive.Although the technology has been widely demonstrated over several decades, itis yet to be shown that it can be diagnostic and improve patient outcomes inclinical applications. We here demonstrate the robustness of pre-polarizing MRI(PMRI) technology for assembly and deployment in developing countries for thespecific application to infant hydrocephalus. Hydrocephalus treatment planningand management requires modest spatial resolution, and only that the brain canbe distinguished from fluid - tissue contrast detail within the brainparenchyma is not essential. We constructed an internally shielded PMRI systembased on the Lee-Whiting coil system with a 22 cm diameter of spherical volume.In an unshielded room, projection phantom images were acquired at 113 kHz within-plane resolution of 3 mm x 3 mm, by introducing gradient fields ofsufficient magnitude to dominate the 5000ppm inhomogeneity of the readoutfield. The low cost, straightforward assembly, deployment potential, andmaintenance requirements demonstrate the suitability of our PMRI system fordeveloping countries. Further improvement in the image spatial resolution andcontrast of low-field MRI will broaden its potential clinical utility beyondhydrocephalus.

Design of a sustainable pre-polarizing magnetic resonance imaging system for infant hydrocephalus