English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Zendy Plus

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Zendy Tools

Zendy Open

Bileaflet mechanical heart valves have one of the most successful valvedesigns for more than 30 years. These valves are often used for aortic valvereplacement, where the geometry of the aortic root sinuses may vary due tovalvular disease and affect valve performance. Common geometrical sinus changesmay be due to valve stenosis and insufficiency. In the current study, theeffect of these geometrical changes on the mean flow and velocity fluctuationsdownstream of the valve and aortic sinuses were investigated. The study focusedon the fully-open leaflet position where blood velocities are close to theirmaximum. Simulation results were validated using previous experimental laserDoppler anemometry (LDA) measurements. Results showed that as the stenosis andinsufficiency increased there were more flow separation and increased localmean velocity downstream of the leaflets. In addition, the detected elevatedvelocity fluctuations were associated with higher Reynolds shear stresseslevels, which may increase the chances of blood damage and platelet activationand may lead to increased risk of blood clot formation.

The Influence of the Aortic Root Geometry on Flow Characteristics of a Bileaflet Mechanical Heart Valve