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The energy-minimization multiscale (EMMS) principle of compromise incompetition is believed to be generally applicable for all mesoscale problemsat different levels in the real world, spanning from elementary particles tothe universe. This stimulated a fundamental proposition of the concept ofmesoscience. This article discusses a potential universality of theregime-specific multi-objective variational feature of this underlyingprinciple through case studies in chemical engineering. It is also elucidatedwhy the currently available variational principles are not applicable to themesoscale problems. The paper concludes with prospects on future study.

Regime-Specific Multi-Objective Variational Principle of Compromise in Competition at Mesoscales