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Dual-functional nanoparticles, with the property of aggregation-inducedemission and the capability of reactive oxygen species, were used to achievepassive/active targeting of tumor. Good contrast in in vivo imaging and obvioustherapeutic efficiency were realized with a low dose of AIE nanoparticles aswell as a low power density of light, resulting in negligible side effects.

Targeted and Imaging-guided In Vivo Photodynamic Therapy of Tumors Using Dual-functional, Aggregation-induced Emission Nanoparticles