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Protein-protein interactions (PPIs) perform important roles on biologicalfunctions. Researches of mutants on protein interactions can further understandPPIs. In the past, many researchers have developed databases that storedmutants on protein interactions, which are old and not updated till now. Toaddress the issue, we developed a kinetic and thermodynamic database of mutantprotein interactions (dbMPIKT) that can be freely accessible at our website.This database contains 5291 mutants that integrated data from previousdatabases and data from literatures for nearly three years. Furthermore, thedata were analyzed, involving mutation number, mutation type, protein pairsource and network map construction. On the whole, the database provides newdata to further improve the study on PPIs. Website:http://210.45.212.128/lqy/index.php

dbMPIKT: A web resource for the kinetic and thermodynamic database of mutant protein interactions