English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Plus monthly

Global: Zendy Tools annual

Global: Zendy Tools monthly

Global: Zendy Free Plan

Since the earliest electroencephalography experiments, large scaleoscillations have been observed in the mammalian brain. More recently, theyhave been identified not only in the cerebral cortex and thalamus, butpervasively in the healthy basal ganglia. The basal ganglia mediatedsynchronization model, introduced here, implicates these oscillations in thecombination of cortical association mechanisms with stimulus-response andreinforcement mechanisms in the basal ganglia. In the core mechanism of themodel, oscillatory patterns in cortex are selected by and routed through thebasal ganglia to the thalamus phase-coherently, then circulated back to widelyseparated areas of cortex, synchronizing those areas and functionallyconnecting them. Corticostriatal and striatonigral conduction delays arecrucial to this mechanism, and evidence suggests that these delays areunusually long, and unusually varied, in arrangements that might facilitatelearning of useful time alignments and associated resonant frequencies. Otherstructural arrangements in the basal ganglia show further specialization forthis role, with convergence in the inputs from cortex, and divergence in manyof the return paths to cortex, that systematically reflect corticocorticalanatomical connectivity. The basal ganglia also target the dopaminergic,cholinergic, and serotonergic centers of the brainstem and basal forebrain, andthe reticular nucleus of the thalamus, structures broadly implicated in themodulation of oscillatory network activity and expressions of plasticity. Bylearning to coordinate these various output channels, the basal ganglia arepositioned to facilitate and synchronize activity in selected areas of cortex,broadly impart selective receptivity, attenuate and disconnect interferingactivity, and recurrently process the resulting patterns of activity,channeling cognition and promoting goal [...]

Control of Functional Connectivity in Cerebral Cortex by Basal Ganglia Mediated Synchronization