English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Plus monthly

Global: Zendy Tools annual

Global: Zendy Tools monthly

Global: Zendy Free Plan

In the applications of the graph theory it is unusual that one considersnumerous, pairwise different graphs on the very same set of vertices. In thecase of human braingraphs or connectomes, however, this is the standardsituation: the nodes correspond to anatomically identified cerebral regions,and two vertices are connected by an edge if a diffusion MRI-based workflowidentifies a fiber of axons, running between the two regions, corresponding tothe two vertices. Therefore, if we examine the braingraphs of $n$ subjects,then we have $n$ graphs on the very same, anatomically identified vertex set.It is a natural idea to describe the $k$-frequently appearing edges in thesegraphs: the edges that are present between the same two vertices in at least$k$ out of the $n$ graphs. Based on the NIH-funded large Human ConnectomeProject's public data release, we have reported the construction of theBudapest Reference Connectome Server \url{http://connectome.pitgroup.org} thatgenerates and visualizes these $k$-frequently appearing edges. We call thegraphs of the $k$-frequently appearing edges "$k$-consensus connectomes" sincean edge could be included only if it is present in at least $k$ graphs out of$n$. Considering the whole human brain, we have reported a surprising propertyof these consensus connectomes earlier. In the present work we are focusing onthe frontal lobe of the brain, and we report here a similarly surprisingdynamical property of the consensus connectomes when $k$ is gradually changedfrom $k=n$ to $k=1$: the connections between the nodes of the frontal lobe areseemingly emanating from those nodes that were connected to sub-corticalstructures of the dorsal striatum: the caudate nucleus, and the putamen. Wehypothesize that this dynamic behavior copies the axonal fiber development ofthe frontal lobe.

The Dorsal Striatum and the Dynamics of the Consensus Connectomes in the Frontal Lobe of the Human Brain