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In this paper, we study the Cauchy problem for the generalized Keller-Segelsystem with the cell diffusion being ruled by fractional diffusion:\begin{equation*} \begin{cases}  \partial_{t}u+\Lambda^{\alpha}u-\nabla\cdot(u\nabla \psi)=0\quad &\mbox{in}\\  \mathbb{R}^n\times(0,\infty),  -\Delta \psi=u\quad &\mbox{in}\ \  \mathbb{R}^n\times(0,\infty),  u(x,0)=u_0(x), \ \ &\mbox{in}\ \ \mathbb{R}^n. \end{cases} \end{equation*} Inthe case that $1<\alpha\leq 2$, we prove local well-posedness for any initialdata and global well-posedness for small initial data in critical Besov spaces$\dot{B}^{-\alpha+\frac{n}{p}}_{p,q}(\mathbb{R}^{n})$ with $1\leq p<\infty$,$1\leq q\leq \infty$, and analyticity of solutions for initial data $u_{0}\in\dot{B}^{-\alpha+\frac{n}{p}}_{p,q}(\mathbb{R}^{n})$ with $1< p<\infty$, $1\leqq\leq \infty$. Moreover, the global existence and analyticity of solutions withsmall initial data in critical Besov spaces$\dot{B}^{-\alpha}_{\infty,1}(\mathbb{R}^{n})$ is also established. In thelimit case that $\alpha=1$, we prove global well-posedness for small initialdata in critical Besov spaces $\dot{B}^{-1+\frac{n}{p}}_{p,1}(\mathbb{R}^{n})$with $1\leq p<\infty$ and $\dot{B}^{-1}_{\infty,1}(\mathbb{R}^{n})$, and showanalyticity of solutions for small initial data in$\dot{B}^{-1+\frac{n}{p}}_{p,1}(\mathbb{R}^{n})$ with $1<p<\infty$ and$\dot{B}^{-1}_{\infty,1}(\mathbb{R}^{n})$, respectively.

Well-posedness and Gevrey Analyticity of the Generalized Keller-Segel System in Critical Besov Spaces