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Purpose: The mechanics of the mitral valve leaflet as a nonlinear, inelasticand anisotropic soft tissue results from an integrated response of manymathematical/physical indexes' that illustrate the tissue. In the past decade,finite element modeling of complete heart valves has greatly aided evaluationof heart valve surgery, design of bioprosthetic valve replacements, and generalunderstanding of healthy and abnormal cardiac function. Such a model must bebased on an accurate description of the mechanical behavior of the valvematerial. It is essential to calculate velocity/displacement and strainrate/strain at a component level that is to work at the cellular level. In thisstudy we developed the first three-dimensional displacement vectors field inthe characterization of mitral valve leaflets in continuum equations ofinelasticity framework based on echocardiography.  Method: Much of our knowledge of abnormal mitral valve function is based onsurgical and post-mortem studies while these studies are quantitative in somecases, they are limited by evaluation of valve anatomy in a fixed andnonfunctioning state. A more sophisticated analysis method is necessary to gaina full considerate of mitral valve function. Several groups attempted to modelmitral valve anatomy and function by mathematical/physical equations.  Result: Preliminary results concerning a different aspect of MVLbiomechanics, such as leaflets dynamics, displacements/velocities and strainrates/strains of points on leaflets, were in good agreement with inechocardiographic observations.

A novel mathematical technique to assess of the mitral valve dynamics based on echocardiography