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In this paper we present a Calder\'{o}n-Zygmund approach for a large class ofparabolic equations with pseudo-differential operators $\mathcal{A}(t)$ ofarbitrary order $\gamma\in(0,\infty)$. It is assumed that $\cA(t)$ is merelymeasurable with respect to the time variable. The unique solvability of theequation $$ \frac{\partial u}{\partial t}=\cA u-\lambda u+f, \quad (t,x)\in\fR^{d+1} $$  and the $L_{q}(\fR,L_{p})$-estimate $$\|u_{t}\|_{L_{q}(\fR,L_{p})}+\|(-\Delta)^{\gamma/2}u\|_{L_{q}(\fR,L_{p})}+\lambda\|u\|_{L_{q}(\fR,L_{p})}\leq N\|f\|_{L_{q}(\fR,L_{p})} $$ are obtainedfor any $\lambda > 0$ and $p,q\in (1,\infty)$.

An $L_q(L_p)$-theory for parabolic pseudo-differential equations: Calder\'on-Zygmund approach