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Accurate physical modeling with 3D-printing techniques could lead to newapproaches to study structure and dynamics of biological systems complementingcomputational methods. Computational biology has become an important part ofresearch over the last couple of decades. Now 3D printing technology opens thedoor for a new field, Physical Biomodeling, at the intersection of experimentaldata, computational biology and physical modeling for study of biologicalsystems, such as protein folding at nano-scale. Here I explore this new domainof precision physical modeling and correlate it with existing visualization andcomputational systems and future possibilities. Dynamic physical models can bedesigned to-scale that can serve as research tools in future along withexisting biocomputational tools and databases, adding a third angle to tackleunsolved scientific problems.

Physical Biomodeling: a new field enabled by 3-D printing in biomodeling