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We study the effect of the non-commutativity on the creation of scalarparticles from vacuum in the anisotropic universe space-time. We derive thedeformed Klein-Gordon equation up to second order in the non-commutativityparameter using the general modified field equation. Then the canonical methodbased on Bogoliubov transformation is applied to calculate the probability ofparticle creation in vacuum and the corresponding number density in the $k$mode. We deduce that the non-commutative space-time introduces a new source ofparticle creation.

Anisotropic universe space-time non-commutativity and scalar particle creation in the presence of a constant electric field