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This article considers the Dissertatio de Arte Combinatoria, published in1666 and relatively neglected by Leibniz s scholars. However in recent timesthe tide seems to be changing. Our work presents three main parts (sections II,III and IV, respectively). The first one exposes the contributions of M. Serresand E. Knobloch, viewed from our stand-point. The second one emphazises therole played by the symmetric group as the underlying mathematical structure ofthe Opus. Finally we treat the caput variationis which, in our opinion, is thefundamental concept of the Dissertatio. Moreover, it is suggested that theimportance of such a theoretical insight may be traced in many aspects ofLeibniz s subsequent thought.

La Dissertatio de Arte Combinatoria de Leibniz en seconde lecture