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Evolution of homonuclear J-coupling during t1 period creates Zero Quantumartefacts which seriously degrade the performance of 2D NOESY. In our previouswork [28], it is demonstrated that creation of such artefacts can be preventedby incorporation of a perfect echo based broadband homo-nuclear decouplingtechnique during t1 period that also allows chemical shift encoding. However,such experiments have limited F1 resolution as the perfect echo baseddecoupling remains efficient for interpulse delay 2{\tau} (=t1) short comparedto 1/J. A solution to this problem is provided in the present work where weshow that even a partial decoupling effect of a perfect echo block for extendedt1 period close to 1/2J greatly suppress the build up of antiphase content andthereby enhances the sensitivity of corresponding NOE cross peaks. The partialdecoupling do lead to generation of partial ZQ coherence which is furthereliminated by application of a ZQ filter.

Zero-Quantum filtered Perfect NOESY: Enhanced sensitivity for NOE cross peaks perturbed by Zero Quantum artefacts