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In this article, the liquid metal GaInSn alloy (67% Ga, 20.5% In, and 12.5%Sn by volume) is proposed for the first time to repair the peripheralneurotmesis as connecting or functional recovery channel. Such material owns agroup of unique merits in many aspects, such as favorable fluidity, supercompliance, high electrical conductivity, which are rather beneficial forconducting the excited signal of nerve during the regeneration process in vivo.It was found that the measured electroneurographic signal from the transectedbullfrog sciatic nerve reconnected by the liquid metal after the electricalstimulation was close to that from the intact sciatic nerve. The controlexperiments through replacement of GaInSn with the conventionally used RigerSolution revealed that Riger Solution could not be competitive with the liquidmetal in the performance as functional recovery channel. In addition, throughevaluation of the basic electrical property, the material GaInSn works moresuitable for the conduction of the weak electroneurographic signal as itsimpedance was several orders lower than that of the well-known Riger Solution.Further, the visibility under the plain radiograph of such material revealedthe high convenience in performing secondary surgery. This new generation nerveconnecting material is expected to be important for the functional recoveryduring regeneration of the injured peripheral nerve and the optimization ofneurosurgery in the near future.

Liquid Metal as Connecting or Functional Recovery Channel for the Transected Sciatic Nerve