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In this paper we motivate and develop a model of gene expression for thepurpose of studying the interaction between synthetic gene circuits and thechassis cell within which they are in- serted. This model focuses on thetranslational aspect of gene expression as this is where the literaturesuggests the crucial interaction between gene expression and shared resourceslies.

Modelling the burden caused by gene expression: an in silico  investigation into the interactions between synthetic gene circuits and their  chassis cell