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In this Communication, we express our reservations on some aspects of theinterpretation of the Lempel-Ziv Complexity measure (LZ) by Mateo et al. in"Interpretation of the Lempel-Ziv complexity measure in the context ofbiomedical signal analysis," IEEE Trans. Biomed. Eng., vol. 53, no. 11, pp.2282-2288, Nov. 2006. In particular, we comment on the dependence of the LZcomplexity measure on number of harmonics, frequency content and amplitudemodulation. We disagree with the following statements made by Mateo et al.  1. "LZ is not sensitive to the number of harmonics in periodic signals."  2. "LZ increases as the frequency of a sinusoid increases."  3. "Amplitude modulation of a signal doesnot result in an increase in LZ."  We show the dependence of LZ complexity measure on harmonics and amplitudemodulation by using a modified version of the synthetic signal that has beenused in the original paper. Also, the second statement is a generic statementwhich is not entirely true. This is true only in the low frequency regime anddefinitely not true in moderate and high frequency regimes.

Comment on 'Interpretation of the Lempel-Ziv Complexity Measure in the context of Biomedical Signal Analysis'