English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Plus monthly

Global: Zendy Tools annual

Global: Zendy Tools monthly

Global: Zendy Free Plan

The shift from outcrossing to self-fertilization is among the most commontransitions in plants. Until recently, however, a genome-wide view of thistransition has been obscured by a dearth of appropriate data and the lack ofappropriate population genomic methods to interpret such data. Here, we presentnovel analyses detailing the origin of the selfing species, Capsella rubella,which recently split from its outcrossing sister, Capsella grandiflora. Due tothe recency of the split, most variation within C. rubella is found within C.grandiflora. We can therefore identify genomic regions where two C. rubellaindividuals have inherited the same or different segments of ancestraldiversity (i.e. founding haplotypes) present in C. rubella's founder(s). Basedon this analysis, we show that C. rubella was founded by multiple individualsdrawn from a diverse ancestral population closely related to extant C.grandiflora, that drift and selection have rapidly homogenized most of thisancestral variation since C. rubella's founding, and that little novelvariation has accumulated within this time. Despite the extensive loss ofancestral variation, the approximately 25% of the genome for which two C.rubella individuals have inherited different founding haplotypes makes uproughly 90% of the genetic variation between them. To extend these findings, wedevelop a coalescent model that utilizes the inferred frequency of foundinghaplotypes and variation within founding haplotypes to estimate that C. rubellawas founded by a potentially large number of individuals 50-100 kya, and hassubsequently experienced a 20X reduction in its effective population size. Aspopulation genomic data from an increasing number of outcrossing/selfing pairsare generated, analyses like this here will facilitate a fine-scaled view ofthe evolutionary and demographic impact of the transition toself-fertilization.

Genomic identification of founding haplotypes reveals the history of the selfing species Capsella rubella