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Relevant events in a three state illness-death model (IDM) of a chronicdisease are the diagnosis of the disease and death with or without the disease.In this article a simulation framework for populations moving in the IDM ispresented. The simulation is closely related to the concept of Lexis diagramsin event history analysis. Details of the implementation and an example of ahypothetical disease are described.

Simulation of Populations in a Time-, Age- and Duration Dependent Illness-Death Model