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The ALICE experiment studies nucleus-nucleus collisions at the LHC in orderto investigate the properties of QCD matter at extreme energy densities. Themeasurement of open charm and open beauty production allows one to probe themechanisms of heavy-quark propagation, energy loss and hadronization in the hotand dense medium formed in high-energy nucleus-nucleus collisions. Inparticular, in-medium energy loss is predicted to be different for masslesspartons (light quarks and gluons) and heavy quarks at moderate momentum. TheALICE apparatus allows us to measure open heavy-flavour particles in severaldecay channels and with a wide phase-space coverage.  We present the results on the nuclear modification factors for heavy-flavourparticle production in Pb-Pb collisions at sqrtsNN=2.76 TeV. Usingproton-proton and lead-lead collision samples at sqrts=2.76 and 7 TeV and atsqrtsNN=2.76 TeV, respectively, nuclear modification factors R_AA(pT) weremeasured for D mesons at central rapidity (via displaced decay vertexreconstruction), and for electrons and muons from heavy-flavour decays, atcentral and forward rapidity, respectively. A large suppression is observed, bya factor 2.5-4 in central Pb--Pb collisions with respect to the pp reference,in the high-pT region, indicating a strong in-medium energy loss of heavyquarks.

Suppression of high-pT heavy-flavour particles in Pb-Pb collisions at the LHC, measured with the ALICE detector