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In this paper, we study global well-posedness of the two-dimensionalKeller-Segel model in Lebesgue space and Sobolev space. Recall that in thepaper "Existence and uniqueness theorem on mild solutions to the Keller-Segelsystem in the scaling invariant space, J. Differential Equations, {252}(2012),1213--1228", Kozono, Sugiyama & Wachi studied global well-posedness of$n$($\ge3$) dimensional Keller-Segel system and posted a question about theeven local in time existence for the Keller-Segel system with$L^1(R^2)\times{L}^\infty(R^2)$ initial data. Here we give an affirmativeanswer to this question: in fact, we show the global in time existence anduniqueness for $L^1(R^2)\times{L}^{\infty}(R^2)$ initial data. Furthermore, weprove that for any $H^1_b(R^2) \times {H}^1(R^2)$ initial data with$H^1_b(R^2):=H^1(R^2)\cap{L}^\infty(R^2)$, there also exists a unique globalmild solution to the parabolic-parabolic Keller-Segel model. The estimates of${\sup_{t>0}}t^{1-\frac{n}{p}}\|u\|_{L^p}$ for $(n,p)=(2,\infty)$ and theintroduced special half norm, i.e.$\sup_{t>0}t^{1/2}(1+t)^{-1/2}\|\nabla{v}\|_{L^\infty}$, are crucial in ourproof.

Global Well-posedness of the Parabolic-parabolic Keller-Segel Model in $L^{1}(R^2)\times{L}^{\infty}(R^2)$ and $H^1_b(R^2)\times{H}^1(R^2)$