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We re-visit the problem of non-perturbative contribution to the massdifference in D0-D0bar mixing within the Standard Model (SM). There are twoknown approaches to take this contribution into account. In the longlong-distance approach one analyzes contribution to the D0-D0bar from exclusivechannels due to production of intermediate charmless hadronic states. In theshort-distance approach one employs the Operator Product Expansion (OPE)techniques with the non-perturbative contribution coming from the diagramscontaining low energy-momentum quark states - quark-antiquark condensates.Within the latter approach, the non-perturbative contribution to the normalizedmass difference in D0-D0bar mixing, x_D = Delta M_D / Gamma_D, is estimated tobe few x 10^{-3}, that is to say very close to the experimental value of x_D.We attempt to verify quantitatively this estimate here. We find that the actualprediction of the short-distance approach is few times less than the estimateabove and order of magnitude less than the experimental value of x_D.

Dominant 1/m_c Contribution To The Mass Difference in D0-D0bar Mixing