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Using the form factors calculated in the three-point QCD sum rules approach,we calculate the new physics contributions to the physical observables of $B_c\to D_s^* \mu^+\mu^-$ decay in the family non-universal $Z^{\prime}$ model.Under the consideration of three cases of the new physics parameters, we findthat: (a) the $Z^{\prime}$ boson can provide large contributions to thedifferential decay rates; (b) the FBA could be increased by about 47%, 38%, and110% at most in S1, S2, and ELV, respectively. In addition, the zero crossingcould be shifted in all the cases; (c) when $\hat{s}>0.08$, the value of $P_L$could be changed from -1 in the SM to -0.5 in S1, and -0.6 in S2, 0 in ELV,respectively; (d) The new physics corrections to $P_T$ would decrease the SMprediction about 25% for the cases of S1 and S2, 100% for the case of ELV.

The rare decay $B_c \rightarrow D_s^* \mu^+ \mu^-$ in a family non-nuiversal model