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The mid-infrared period-luminosity (P-L) relation for Cepheids will beimportant in the JWST era, as it holds the promise of deriving the Hubbleconstant within 2% accuracy. We present the synthetic P-L and period-color(P-C) relations, derived from a series of stellar pulsation models with varyinghelium and metallicity abundance, in the Spitzer IRAC bands. Selected syntheticP-L and P-C relations were compared to the empirical relations derived fromGalactic and Large Magellanic Cloud Cepheids. We also present the empirical P-Lrelations based on the latest distance measurements using infrared surfacebrightness techniques.

Synthetic Cepheid Period-Luminosity & Period-Color Relations in Spitzer's IRAC Bands