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We examine the effect of including the `combined' HERA structure functiondata in the MSTW global fit for parton distribution functions (PDFs). Thecombined neutral-current HERA data have a significant, if not dramatic, effect,of up to 2--3% at NLO for Z boson and Higgs production at the Tevatron and LHC,and a generally slightly smaller effect, particularly on LHC processes, atNNLO. This is an amount comparable, or less than, the typical PDFuncertainties, and hence we do not intend to release an imminent update to theMSTW 2008 fit. We also investigate the consistency with the recent D0 data onelectron and muon charge asymmetry from W decays and the direct CDF measurementof the W charge asymmetry. The D0 lepton charge asymmetry data imply a fairlylarge change to the down-quark distribution and/or large nuclear corrections tobe applied when fitting to deuterium structure function data, while the CDF Wcharge asymmetry data are more consistent with the existing PDFs. However, itis difficult to reconcile all of the Tevatron W -> lepton neutrino chargeasymmetry data sets with the fit, and to some extent, with each other.

The effects of combined HERA and recent Tevatron W - > lepton neutrino charge asymmetry data on the MSTW PDFs