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Tissue and water equivalence of some phantom materials originally developedfor conventional radiation therapy was investigated on the ITEP medical protonbeam facility. The proton CSDA range in three variants of Plastic Water, lung,adipose, muscle and compact bone substitute materials (CIRS Inc., USA) wasmeasured by a silicon diode as well as the residual proton range in liquidwater after passing a slab of each material under investigation. In addition,the proton range in five materials of known elemental composition wascalculated by Monte Carlo technique. The obtained results were compared withreference data from ICRU report 49 for respective biological tissues and water.A total uncertainty of the proton range ratios was estimated to be from 0.9 to1.5% (1SD). Within these uncertainties, Plastic Water, Plastic Water LR,Plastic Water DT, muscle and compact bone demonstrated a good agreement withthe reference data. The range in adipose and lung substitutes is a few percentslower than that in the respective tissues.

Tissue equivalence of some phantom materials for proton beams