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Series of tetrahydrobenzo[b]thiophen-2-yl)-N, N-dimethylformamidine derivatives were synthesized from 2-amino-4, 5, 6,7-tetrahydrobenzo[b]thiophene-3-carbonitrile. The new derivatives were checked good antimicrobial activities against S. aureus, E. coli and C. albicans, and A. Niger microbes.

Synthesis of (3-Cyano-4, 5, 6, 7-Tetrahydrobenzo [B] Thiophen-2- Yl) Formamidine Derivatives as Effective Antimicrobial Agents