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Inhibitory compound of α-glucosidase bioactivity was isolated from Ethanol extract of the stem bark of Raru ( Vatica pauciflora Blume) which, is a wild plant that grows in Tapanuli state in Indonesia.The ethanol extract of the stem bark of raru was partitioned and was chromatographed on columns with stationare fase silica gel 60 mesh F 254 (0,063 mm – 0,200 mm). The ethanol extract of isolates showed the enzyme α-glucosidase inhibitor IC 5 0 of  93.46. The next step is the determination of the chemical structure of the UV Vis,  FT-IR, NMR,  (COSY, HMQC and HMBC). It found of compounds consist  of 2 methoxy, 1 aromatic, and 1 carbonil compounds. The Isolat is a 3,4,9,Trihidroxy-2-(hydroxymethyl)-8-10-dimethoxy-2-3-4atetrahydropyrano(3,2-c)isochromen-6(10bH)-one acording to IUPAC.

Identification Of Chemistry Bioactivity Structure Of Α- Glucosidase Inhibitor From Ethanol Extract Of The Stem Bark Raru (Vatica Pauciflora Blume)