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Microwave-assisted efficient and eco-friendly synthesis of bis-, tris(indolyl)methanes and di- bis(indolyl)methanes by the reaction of indoles with aldehydes in presence of fruit juice of Citrus limon as catalyst under under solvent-free conditions is reported. The advantages of the protocol are the use of green and inexpensive catalyst, commercially available precursors, simple work-up procedures, high yields and short reaction times.

iosr journal of applied chemistry

Microwave-assisted eco-friendly synthesis of bis-, tris(indolyl)methanes and synthesis of di-bis(indolyl)methanes catalyzed by fruit juice of Citrus limon under solvent-free conditions