English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Calcium dynamics in oocytes plays an important role in oocyte maturation. The calcium concentration is regulated at high levels in oocytes through various mechanisms in order to meet the requirements of oocyte maturation. The understanding of these mechanisms are crucial in understanding the processes of reproduction. In this paper an attempt has been made to develop a finite element model of calcium dynamics in oocyte. The model incorporates the parameters like diffusion coefficient, leak from Endoplasmic Reticulum(ER), and buffers namely 1,2-bis(o-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid(BAPTA) and ethylene glycol-bis(2-aminoethylether)-N,N,N',N'-tetraacetic acid(EGTA). The proposed model is solved numerically using appropriate initial and boundary conditions. A program has been developed in MATLAB 7.11 for the entire problem and simulated on a 32-bit machine to compute the numerical results. The effect of BAPTA, EGTA and Leak from ER is studied in the neighbourhood of L-type calcium channel on calcium distribution in oocyte.

Finite Element Model to Study Effect of Buffers Along With Leak from ER on Cytosolic Ca2+ Distribution in Oocyte