English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Many cell types encode signals in the frequency component of calcium oscillations. In non-excitable cells calcium oscillations are induced by calcium influx from inositol trisphosphate receptors (IP3R) or/and ryanodine receptors (RyR). The frequency of Calcium oscillations induced in such cases is primarily by the way intracellular stores like endoplasmic reticulum, sarco-endoplasmic reticulum are refilled. Sarco-endoplasmic reticulum calcium ATPase (SERCA) is the major pathway by which this refilling process is effected. Most of the mathematical models proposed thus far used Michaelis-Menten kinetics to formulate SERCA pump. In this paper more emphasis has been given over the mathematical formulation of SERCA pump. In particular reverse quasi steady-state approximation (rQSSA) is used to formulate SERCA pump. Comprehensive comparative analysis is performed with the previous SERCA pump formulation. An apparent increase in frequency and amplitude of calcium oscillation is observed. Keywords - SERCA, Michelis-Menten, rQSSA, Enzyme Kinetics.

An Application of Reverse Quasi Steady State Approximation over SERCA