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Radiotherapy is using of ionizing radiation in the treatment of cancer. The aim of radiotherapy is to annihilate the tumor tissue while minimizing damage to the normal surrounding tissues. We can do that by using shielding like custom blocks and MLCs. Uses the MLCs now in all the sites, but does not use blocks except in the necessity of it, as there are different types of MLCs in thickness (1 cm and 0.5 cm, and finally 0.3 cm). The MLCs are not limited to the use of three-dimensional planning only, but also using in the most modern techniques like IMRT and IGRT. When shaping the radiotherapy treatment field size of the tumor, there are some concepts must be included in the accounts, such as the concept of penumbra and radiotherapy field size and the impact of change that field size on the dose distribution within the tumor and dose receiving by OARs. When the field size is shaped where the MLCs ends are attached with tumor (the MLCs margin = 0.0 cm) the penumbra effects on the tumor cover percentage, so the distance between tumor and MLCs ends (MLC margins) must be existing to overcome the penumbra effects. To determine the most adequate MLC margins which achieve the tumor dose coverage a many plans with difference MLC margins were compared from 0.0 cm to 1.2 cm the comparison included the tumor coverage percentage and the received dose to OARs and if it under tolerance or not. After that we can selection the best MLC margins to work out in most famous techniques for pancreas cases. Results: the tumor is not cover when the MLC margins less than 0.5 cm, and from MLC margins 0.5 cm to 0.7 cm the tumor is cover very well and OARs are under tolerance, the MLC margins more than 0.7 cm the tumor cover is very well but OARs received unnecessary doses. After 1.2 cm MLC margin, the saturation occurs of the tumor cover percentage. Conclusions: The best MLC expansion apertures for the radiotherapy of pancreas cancer are from 0.5 cm to 0.7 cm.

A Dosimetric study of different MLC expansion aperture For the radiotherapy of pancreas cancer