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Effects of “Baygon” (a combination of proporxur, dichlorovos and cyfluthrin) on serum and liver enzymes of albino rats were determined using standard scientific methods, after exposure to the insecticide. Twenty five rats were used for the study and grouped into five according to exposure time that ranged from zero (control) to 1440 minutes. Mean serum and liver alkaline phosphatase activities of the experimental animals increased significantly (p<0.05) upon exposure to the insectside. However, the activity in group E exposed for 1440 minutes showed no significant difference (p>0.05) in both the serum and liver homogenate. This is indicative of possible recovery over time. The mean activities of serum and liver acid phosphatase showed no significant difference (p>0.05) relative to the control. Prostatic acid phosphatase increased upon exposure but decreased with time in the serum. Thus exposure to Baygon insecticide for even a short time alters liver enzymes activities and by extension, liver function. These distortions and fluctuations in activities of the liver enzymes in the serum and liver homogenates after exposure to Baygon insecticide is an indication of hepatotoxic effect of the insecticides while the results observed after prolonged exposure showed that there was possible recovery with time.

Effect of Baygon Insecticide on the Activities of Total, Alkaline and Acid Phosphatases of Selected Tissues of Albino Rats