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This research assessed some of the mineral elements present in the mesocarp of the fruit of Balanites aegyptiaca and the effect of the fruits consumption on the serum electrolytes and kidney tissue enzymes of Carbon tetrachloride (CCl4) treated rats. Sixty white albino rats (Rattus norvegicus) with average weight of 150 ± 11.45g assigned to four (4) groups were used to assess the effect of the aqueous extract of the mesocarp of the fruit Balanites aegyptiaca on the rats. Group 1 were the normal control (Nc), group 2 were the diseased control (Dc) group, group 3 and 4 are the test groups of animals orally administered with 0.08mgKgof raw (Tr) extract and 0.19mg/kg of concentrated (Tc) extracts daily. The methods used were cell fractionation, homogenization, centrifugation and spectrophotometry. Magnesium (10.07±0.03ppm), Iron (5.3±0.50ppm), selenium (4.89±1.26ppm), copper (2.47±0.19ppm) and potassium (1.77±0.06ppm) were the major composition of determined minerals. The ash content was found to be 30.98±0.021% of the fruit mesocarp. The serum electrolytes showed that there was significant increase (p<0.05) in the serum calcium, potassium, and sodium ions of tested rats compared to the control rats. Also there were elevations in the level of total proteins, albumin and conjugated bilirubin, the kidney tissue specific enzymes activities (alanine transaminase and alkaline phosphatase) indicated a significant reduction (p<0.05) in levels on the test groups of rats compared to the diseased control. The result of this study shows some mineral elements in the fruit mesocarp of Balanites aegyptiaca, and their effects in the serum electrolytes and kidney tissue enzymes.

Effect of Determined Mineral Elements in Mesocarp of Balanites Aegyptiaca Fruit on Serum Electrolytes of Ccl4 Treated Rats