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In the commercial market, medicinal herbs are used as raw drugs, extracts or tinctures. Isolated active constituents are used for applied research. Medicinal herbs are significant source of hepatoprotective drugs, Eclipta prostrata. L. with active principle Wedelolactone is the prime focus. In the present study to derive hepatoprotective drug, the herb E. prostrata was grown in the Periyar Maniammai College Campus, Vallam and 1kg of the plant leaves were collected and shade dried. Dried and powdered maetria l of E. prostrata was extracted with 80% ethanol. The active principle was isolated and identified by chromatographic technique. The protective effect of E. prostrata on Carbon tetrachloride induced acute liver damage was also studied with male wistar albino rats (180-230g). The protective effect was also undergone for histological studies.

Efficacy Studies of Hepatoprotective Drug Isolated from Eclipta prostrata. L.