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Allium Cepa has been used in folk medicine for treatment of tumors and to relieve dropsy (heart failure related edema). This present study was conducted to determine the effects of the aqueous extract of onion (Allium cepa) on Blood parameters in Wistar rats. Eighteen (18) rats (105 - 158 g) were randomly selected into 3 groups of 6 animal (n = 6) each, Group A served as the control received 1 ml of distilled water while Group B received 45 mg/kg body weight of onion juice and Group C received 20 mg/kg body weight of onion juice extracts for 21 days of experimental period. Animals were sacrificed by cervical dislocation 24 hours after the last administration and blood samples were collected via the retro-orbital route with the aid of a capillary tube, into an EDTA bottle for analysis. The result shows that the juice extracts at various doses significantly (p<0.05) increase the total white blood cell counts, Lymphocyte count, Neutrophils count, also there was a significant (p<0.05) increase in the red blood cell count in rats treated with onion juice. The packed cell volume of rats treated with onion extract were significantly (p<0.05) increased. There was no significant (p˃0.05) increase in the Platelet count, Monocytes count, Eosinophil count, Basophil count of the rats in all groups. Allium cepa

Effects of Aqueous Extract of Onion (Allium cepa) on Blood Parameters in Adult Wistar Rats (Rattus novergicus)