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In this study the effect of different concentrations of anti-GTFIb antibody was tested on the growth of Streptococcus sobrinus serotype G N10 strain and the enzymatic activity of purified GTF-Ib enzyme which was isolated from the Streptococcus sobrinus serotype G N10 strain. It was found that different concentrations of these compounds and the antiGTF-Ib antibody were able to inhibit the enzymatic activity of the purified GTF-Ib with an exception of EDTA. The result was proved that antiGTFIb antibody at concentration of (1.5x10 ml/ mol) has a great influence to inhibit (87.33%) of the enzymatic activity of the purified GTF Ib enzyme followed by sodium fluoride (18ml M), chlorohexidine (20ml M) and ZAK mouthrins which were able to inhibit (81.64%), (75.55%) and (60.40%) respectively from the enzymatic activity of purified GTFIb enzyme.

iosr journal of pharmacy and biological sciences

The Effects of anti-Glucosyltransferase (anti-GTF-Ib) antibody on Growth of Mutans Streptococci Streptococcus sobrinus (serotype G) N10 Strain and Purified GTF-Ib enzyme activity