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The dietary calcium to reduce the uptake of Cadmium concentration O.mossambicus with emphasis on biochemical and histopathological analysis is projected in this work. The values of 24, 48, 72 and 96 h LC50 of Cadmium to tilapia were 47, 97, 123 and 175 ppm respectively. Therefore, cadmium concentration tested in the sub lethal experiment was 17.5 ppm which corresponds to 10 % of the 96 h LC50. Fish were fed with 0, 10 and 50 mg Ca 2+ g -1 food for a month. In the liver, there were blood congestion in sinusoids, vacuolation of hepatocytes and necrosis. In the gills of Cd treatment, edema, lamellar cell hyperplasia, epithelial lifting, lamellar fusion and aneurysm were observed. In the kidney, glomerulus's atrophy, tubular swelling and necrosis were seen. The structural damages may be correlated to the significant increase (p≤0.05) in aminotransferase activities. Fish fed with Ca 2+ supplemented diets showed a significant alteration when compare with Cd treatment groups. These results indicated that dietary Ca 2+ shall be protective in reducing Cd uptake and accumulation in fish exposed to environments contaminated with waterborne Cd.

A Dietary Chemical Study of the Protection of Calcium against Cadmium Uptake in Freshwater Fish.