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Little is known about host immunodynamics during Brucellosis. We conducted immunohematological study in Brucellosis affected cattle for 3 months. Serum proteins and globulins were decreased very significantly (P<0.01) from zero day (0D) to 90D and significantly (P<0.05) from 0D to 30D. Globulins decreased significantly (P<0.05) from 0D to 75D. Titers of anti-Brucella antibodies by Standard Tube Agglutination Test, Microagglutination Test and Indirect Hemagglutination did not differ significantly among themselves from 0D to 90D. However, in ELISA, there was a very significant (p<0.01) increase in titers from 0Day to 60D, 75D and 90D; from 30Day to 60D, 75D and 90D; and from 45Day to 60D, 75D and 90D, respectively. Levels of leukocytes, lymphocytes and neutrophils did not differ significantly. However, monocyte levels increased from 45D to 60D and then decreased from 60D to 75D significantly (P<0.05). Data reflects the immunohematological dynamics in response to disease and provides insight for suitable intervention.

A Cohort Study on Some Immunohematological Parameters in Brucellosis Affected Cattle