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The extensive use of antibiotics in livestock has contributed to the development of antibiotics resistant bacteria and residue deposition in food of animal origin. Alternative to antibiotics use for animal health and welfare as well as food safety is essential for global antibiotic resistance control. The effect of a commercially available monoculture yeast probiotics (Antox®) on the growth performance and inhibition of gut salmonella was carried out in this study.One hundred, one- day-old broiler chicks were randomly distributed into four groups for dosing of a probiotic (containing Saccharomyces cerevisiae) and inoculation with Salmonella gallinarum. The chickens were grouped into four vis: Group 1(control): not dosed with Antox® and not inoculated with Salmonella; Group 2: dosed with Antox® and inoculated with Salmonella; Group 3: dosed with Antox® only; Group 4: inoculated with Salmonella only. The growth performance of the chickens, feed intake (FI) and feed conversion rate (FCR) were monitored weekly throughout the experiment. This study showed improved growth performance of the chicken in live and carcass weight as well as reduced caecal Salmonella load by the yeast probiotic. Probiotic group had significantly (p<0.01) higher body weights compared to the control and Salmonella groups. FI was significantly (p<0.05) higher in the probiotic group, and significant (p<0.01) different from the control and Salmonella infected groups. Higher FCR was recorded in the control group than in probiotic-supplemented groups. Also the caecal Salmonella load of the probiotic group (2.404 log10cfu/g) was significantly lower (p<0.001) than in the Salmonella infected groups. This study confirmed that yeast probiotic improved body weight, feed intake, better feed conversion ratio in broiler chickens and also effectively inhibited the colonization of ceacal salmonella. Its application can replace the use of antibiotics as growth promoters and reduce the incidence of Salmonella and antibiotic resistance in poultry and should be promoted for adoption by commercial poultry farms.

Effects of Commercial Yeast Probiotic (Antox® Supplement) On Broiler Chickens Growth Performance and Salmonella Inhibition