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Surgical site infection is a kind of health care related infection which a wound illness occurs following to an invasive surgical process. Aim of study: Compare between using of chlorhexidine gluconate versus povidone iodine for skin preparation to avoid infection after cardiothoracic surgery. Setting of study: Cardio thoracic surgery department at Mansura University Hospital. Methods: Design: Quasi experimental designs comparative following up study. Subjects: 70patients were selected randomly and alternatively into two equivalent groups, 35 patients for every group. Tools: Two tools were used for study, Tool 1: Patients bio-sociodemographic data, contain of two parts, tool 2: Wound infection assessment: involved of 3 parts. Results: The most signs, symptoms and side effects of surgical site infection appeared in povidone group more than chlorhexidine group as well as there were organisms like staph auras presented in povidone group and no organisms presented in chlorhexidine group. Conclusions: the incidence of SSI with povidone iodine more than chlorhexidine group. Recommendations: chlorhexidine gluconate with alcohol should be used to prevent of SSI.

Comparison between Uses of Chlorhexidine Gluconate versus Povidone Iodine for Skin Preparation to Prevent Infection after Cardiothoracic Surgery