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Cryptococcal meningitis is the most common lethal opportunistic fungal infection caused by a fungus (yeast) - Cryptococcus neoformans in people with HIV and AIDS. Cryptococcal infection affects approximately one million HIV-infected patients worldwide each year, and is associated with high mortality. In Sub-Saharan Africa, Cryptococcal disease has been associated with 17% of all deaths among HIV-infected patients and 75% of deaths from opportunistic infections in men with pulmonary tuberculosis. Prompt treatment depends on awareness of the common symptoms. In Sub-Saharan Africa, Kenya included, data on the prevalence of Cryptococcal infection is scanty. This cross-sectional study carried out at Kapkatet District Hospital Comprehensive Care Clinic (CCC) using 300 selected HIV patients enrolled for review at the CCC from June to August 2012 sought to identify HIV infected patients who also had Cryptococcus neoformans as detected from their blood samples. Serum samples were studied for the detection of capsular polysaccharide antigen of Cryptococcus neoformans usinglatex agglutination technique with pronase pre-treatment (IMMY, Crypto-Latex Antigen Detection System, Immunomycologics Inc., OK, USA). Results showed that 1% of the patients were confirmed to have Cryptococcus Neoformans. Of those found positive, 25% were males and 75% were females and were distributed between ages 21 and 50 years which also showed that 73% of all patients who participated in the study were in this age range. Since Cryptococcosis is highly lethal once contracted, health care workers managing people living with HIV/AIDS need to have ahigh index of suspicion so as to initiate prompt treatment immediately the disease is confirmed. Abbreviations And Acronyms

Detection of Cryptococcus Neoformans Amongst HIV Patients Attending Comprehensive Care Clinic At Kapkatet District Hospital, Kenya