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Context: Recently Candidiasis has become one of the major nosocomial infections among hospitalized neonates. Several Candida species can give rise to same clinical presentation but their antifungal susceptibility patterns may vary. Aim and Objectives: The aim of the present study is to assess the risk factors contributing to neonatal oral candidiasis, identification of its causative species and determination of antifungal susceptibility patterns. Settings and Design: This case control study was performed to determine the causative species and risk factors of neonatal candidiasis among the neonates admitted to neonatal care unit. Materials and Methods: Swabs from oral thrush of 119 neonates were collected, same number of age and sex matched neonates were examined as control. Blood culture was also performed in suspected cases of candidemia. Swabs were collected from the hands of 28 health care workers and 58 mothers and all the relevant data was collected. After doing speciation antifungal susceptibility test was performed for 94 pure isolates. Statistical analysis used: All the results were analyzed using RaoSOFT , the result was expressed as mean ± SD and p value < 0.05 was considered significant.

Risk Factor Determination and Antifungal Susceptibility Patterns of Candida in Neonatal Oral Candidiasis